Automated hypothesis generation and testing using large language models. Use this skill when generating scientific hypotheses from datasets, combining literature insights with empirical data,...

Coordinate development workflows across multiple Git repositories with synchronized branching, batch commits, cross-repo operations, and monorepo-like workflows for microservices and multi-package...

Create distinctive, production-grade frontend interfaces with high design quality. Use this skill when the user asks to build web components, pages, or applications. Generates creative, polished...

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Query PubChem via PUG-REST API/PubChemPy (110M+ compounds). Search by name/CID/SMILES, retrieve properties, similarity/substructure searches, bioactivity, for cheminformatics.

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Query CZ CELLxGENE Census (61M+ cells). Filter by cell type/tissue/disease, retrieve expression data, integrate with scanpy/PyTorch, for population-scale single-cell analysis.

Access RCSB PDB for 3D protein/nucleic acid structures. Search by text/sequence/structure, download coordinates (PDB/mmCIF), retrieve metadata, for structural biology and drug discovery.

Enhance uxscii components from sketch to production fidelity. Use when working with .uxm files marked as "fidelity: sketch" or when user wants to add detail and polish to components.

Add interaction states like hover, focus, disabled, active, error to existing uxscii components. Use when working with .uxm files, when user wants to expand, enhance, or add states to .uxm components.

Query openFDA API for drugs, devices, adverse events, recalls, regulatory submissions (510k, PMA), substance identification (UNII), for FDA regulatory data analysis and safety research.

Use when creating or editing skills, before deployment, to verify they work under pressure and resist rationalization - applies RED-GREEN-REFACTOR cycle to process documentation by running...

Therapeutics Data Commons. AI-ready drug discovery datasets (ADME, toxicity, DTI), benchmarks, scaffold splits, molecular oracles, for therapeutic ML and pharmacological prediction.

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Use when errors occur deep in execution and you need to trace back to find the original trigger - systematically traces bugs backward through call stack, adding instrumentation when needed, to...

PostgreSQL + Redis database design patterns. Use for data modeling, indexing, caching strategies. Covers JSONB, tiered storage, cache consistency.

This skill should be used when working with reinforcement learning tasks including high-performance RL training, custom environment development, vectorized parallel simulation, multi-agent...

Use when starting any conversation - establishes mandatory workflows for finding and using skills, including using Skill tool before announcing usage, following brainstorming before coding, and...

Jest testing patterns, factory functions, mocking strategies, and TDD workflow. Use when writing unit tests, creating test factories, or following TDD red-green-refactor cycle.