Query ClinicalTrials.gov via API v2. Search trials by condition, drug, location, status, or phase. Retrieve trial details by NCT ID, export data, for clinical research and patient matching.

Evaluate research rigor. Assess methodology, experimental design, statistical validity, biases, confounding, evidence quality (GRADE, Cochrane ROB), for critical analysis of scientific claims.

Use when receiving code review feedback (especially if unclear or technically questionable), when completing tasks or major features requiring review before proceeding, or before making any...

Expert helper for bash scripting, debugging, and best practices

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Query NCBI ClinVar for variant clinical significance. Search by gene/position, interpret pathogenicity classifications, access via E-utilities API or FTP, annotate VCFs, for genomic medicine.

Foundational plotting library. Create line plots, scatter, bar, histograms, heatmaps, 3D, subplots, export PNG/PDF/SVG, for scientific visualization and publication figures.

Validate, format, and work with JSON configuration files

Use when implementation is complete, all tests pass, and you need to decide how to integrate the work - guides completion of development work by presenting structured options for merge, PR, or cleanup

Automated network troubleshooting and diagnostics for WSL/Linux environments

Direct REST API access to KEGG (academic use only). Pathway analysis, gene-pathway mapping, metabolic pathways, drug interactions, ID conversion. For Python workflows with multiple databases,...

Frontend development guidelines for React/TypeScript applications. Modern patterns including Suspense, lazy loading, useSuspenseQuery, file organization with features directory, MUI v7 styling,...

Guide for creating high-quality MCP (Model Context Protocol) servers that enable LLMs to interact with external services through well-designed tools. Use when building MCP servers to integrate...

Fast DataFrame library (Apache Arrow). Select, filter, group_by, joins, lazy evaluation, CSV/Parquet I/O, expression API, for high-performance data analysis workflows.

Use when partner provides a complete implementation plan to execute in controlled batches with review checkpoints - loads plan, reviews critically, executes tasks in batches, reports for review...

Systematic framework for evaluating scholarly and research work based on the ScholarEval methodology. This skill should be used when assessing research papers, evaluating literature reviews,...

Create uxscii components with ASCII art and structured metadata when user wants to create, build, or design UI components. Use when working with .uxm files, when user mentions .uxm components, or...

Multi-objective optimization framework. NSGA-II, NSGA-III, MOEA/D, Pareto fronts, constraint handling, benchmarks (ZDT, DTLZ), for engineering design and optimization problems.

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Expert helper for Docker containers, Docker Compose, and container optimization