Use when a user asks for a plan for a coding task, to generate a clear, actionable, and atomic checklist.

Access AlphaFold's 200M+ AI-predicted protein structures. Retrieve structures by UniProt ID, download PDB/mmCIF files, analyze confidence metrics (pLDDT, PAE), for drug discovery and structural biology.

Direct REST API access to UniProt. Protein searches, FASTA retrieval, ID mapping, Swiss-Prot/TrEMBL. For Python workflows with multiple databases, prefer bioservices (unified interface to 40+...

Validate, format, and troubleshoot YAML configuration files

Prisma ORM expert for schema design, migrations, query optimization, relations modeling, and database operations. Use PROACTIVELY for Prisma schema issues, migration problems, query performance,...

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Expert patterns for Plaid API integration including Link token flows, transactions sync, identity verification, Auth for ACH, balance checks, webhook handling, and fintech compliance best...

Infer gene regulatory networks (GRNs) from gene expression data using scalable algorithms (GRNBoost2, GENIE3). Use when analyzing transcriptomics data (bulk RNA-seq, single-cell RNA-seq) to...

Use when building Rails 7+ web applications with Hotwire, real-time features, or background job processing. Invoke for Active Record optimization, Turbo Frames/Streams, Action Cable, Sidekiq.

Query ChEMBL's bioactive molecules and drug discovery data. Search compounds by structure/properties, retrieve bioactivity data (IC50, Ki), find inhibitors, perform SAR studies, for medicinal chemistry.

Use when creating or developing, before writing code or implementation plans - refines rough ideas into fully-formed designs through collaborative questioning, alternative exploration, and...

Use when adding docstrings, creating API documentation, or building documentation sites. Invoke for OpenAPI/Swagger specs, JSDoc, doc portals, tutorials, user guides.

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Best practices for Remotion - Video creation in React

Frontend development patterns for React, Next.js, state management, performance optimization, and UI best practices.

Medicinal chemistry filters. Apply drug-likeness rules (Lipinski, Veber), PAINS filters, structural alerts, complexity metrics, for compound prioritization and library filtering.

Deep web scraping, screenshots, PDF parsing, and website crawling using Firecrawl API

Opinionated frontend development standards for modern React + TypeScript applications. Covers Suspense-first data fetching, lazy loading, feature-based architecture, MUI v7 styling, TanStack...

Generate testable hypotheses. Formulate from observations, design experiments, explore competing explanations, develop predictions, propose mechanisms, for scientific inquiry across domains.

Test authenticated routes in the your project using cookie-based authentication. Use this skill when testing API endpoints, validating route functionality, or debugging authentication issues....